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Welcome to the  Macromolecular Crystallization Laboratory
   

MCL's Mission

The Macromolecular Crystallization Laboratory (MCL) was established within the Department of Chemical and Environmental Engineering in 1997. The mission of the MCL is to engage in fundamental and applied research on, and train engineers and scientists in, all aspects of the crystallization of biological macromolecules, in collaboration with other laboratories at UT and elsewhere. The research areas include crystal growth mechanisms, crystal quality measurements, phase diagrams, and crystallization of novel proteins. The goal of these efforts is to have a significant impact in the fields of structural biology, bioseparations and drug design through research on crystallization.

Contact Information

Director's (Dr. Arunan Nadarajah)   Phone: (419) 530-8031,     Fax: (419) 530-8086
Email: arunan.nadarajah@utoledo.edu
Laboratory Phones: (419) 530-8108  and   (419) 530-8104,     Laboratory Fax: (419) 530-3910
Address: MCL, Department of Chemical & Environmental Engineering, 3048 Nitschke Hall, University of Toledo, Toledo, Ohio 43606-3390.

An Introduction to Protein Crystallization

We are often asked to explain various topics related to protein crystallization.  We have assembled here brief descriptions on some of these topics.  Suggestions for other topics are welcome.

What is Protein Crystallization?
What is an Atomic Force Microscope? 
What is Site-directed Mutagenesis?
What are the Protein Crystal Growth Mechansims?
What is Periodic Bond Chain Theory?

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Macromolecular
Crystallization
Laboratory

Chemical &
Environmental
Engineering

UT
College of
Engineering

The
University
of Toledo

Macromolecular Crystallization Lab

Dept of Chem and Env Engineering

UT College of Engineering

University of Toledo